ELK Biotechnology CCR5 rabbit pAb
CCR5 rabbit pAb는 인간, 마우스, 랫트에서 반응하는 폴리클로날 항체로, WB 및 ELISA에 적합합니다. HIV-1 융합 코리셉터로 알려진 CCR5 단백질 검출에 사용되며, 세포막 단백질 연구에 유용합니다. -20°C에서 1년 보관 가능합니다.
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology CCR5 rabbit pAb
제품명
CCR5 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | C-C chemokine receptor type 5 (C-C CKR-5), CC-CKR-5, CCR-5, CCR5, CHEMR13, HIV-1 fusion coreceptor, CD antigen CD195 |
| Applications | WB, ELISA |
| Recommended Dilutions | WB: 1:500–2000, ELISA: 1:10000–20000 |
| Immunogen | Synthesized peptide derived from human CCR5 Polyclonal |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 40 kD |
| Gene ID (Human) | 1234 |
| Human Swiss-Prot No. | P51681 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human, Mouse, Rat |
Background
This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. This protein is expressed by T cells and macrophages, and is known to be an important co-receptor for macrophage-tropic virus, including HIV, to enter host cells. Defective alleles of this gene have been associated with HIV infection resistance. The ligands of this receptor include monocyte chemoattractant protein 2 (MCP-2), macrophage inflammatory protein 1 alpha (MIP-1 alpha), macrophage inflammatory protein 1 beta (MIP-1 beta), and regulated on activation normal T expressed and secreted protein (RANTES). Expression of this gene was also detected in a promyeloblastic cell line, suggesting that this protein may play a role in granulocyte lineage proliferation and differentiation. This gene is located at the chemokine receptor cluster region.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.