
ELK Biotechnology AVP Receptor V2 rabbit pAb
AVP Receptor V2 rabbit pAb은 인간 및 마우스 시료에 반응하는 다클론 항체로, WB와 ELISA에 적합합니다. 인간 AVP Receptor V2에서 유래한 합성 펩타이드를 면역원으로 사용하며, 세포막 단백질 검출에 유용합니다. 고농도(1 mg/ml) IgG 형태로 -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology AVP Receptor V2 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | AVP Receptor V2 rabbit pAb |
| Alternative Names | Vasopressin V2 receptor (V2R), AVPR V2, Antidiuretic hormone receptor, Renal-type arginine vasopressin receptor |
| Applications | WB, ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthesized peptide derived from human AVP Receptor V2 (AA range: 1–50) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 57 kD |
| GeneID (Human) | 554 |
| Human Swiss-Prot No | P30518 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein |
| Species Reactivity | Human, Mouse |
Background
This gene encodes the vasopressin receptor type 2 (V2 receptor), a member of the seven-transmembrane-domain G protein-coupled receptor (GPCR) superfamily. It couples to Gs proteins, stimulating adenylate cyclase. The V2 receptor is part of a conserved subfamily that includes V1a, V1b, oxytocin, isotocin, and mesotocin receptors. It binds cyclic nonapeptide hormones and is expressed in kidney tubules—particularly the distal convoluted tubule and collecting ducts—where it responds to arginine vasopressin (AVP) to regulate urine concentration and water homeostasis. Loss of this gene’s function results in Nephrogenic Diabetes Insipidus.
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