ELK Biotechnology 6CKine rabbit pAb
6CKine(CCL21) 단백질을 인식하는 토끼 폴리클로날 항체로, IHC, IF, ELISA에 적합합니다. 인간, 쥐, 랫트 시료에 반응하며, 고순도 IgG 형식으로 제공됩니다. -20°C에서 1년간 안정적으로 보관 가능합니다.
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ELK Biotechnology 6CKine rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | 6CKine rabbit pAb |
| Alternative Names | C-C motif chemokine 21 (6Ckine; Beta-chemokine exodus-2; Secondary lymphoid-tissue chemokine; SLC; Small-inducible cytokine A21) |
| Applications | IHC, IF, ELISA |
| Recommended Dilutions | IHC-p: 1:50–200, ELISA: 1:10,000–20,000 |
| Immunogen | The antiserum was produced against synthesized peptide derived from the internal region of human CCL21 (AA range: 71–120). |
| Host | Rabbit |
| Storage | -20°C for 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Gene ID (Human) | 6366 |
| Human Swiss-Prot No. | O00585 |
| Cellular Localization | Secreted |
| Species Reactivity | Human, Rat, Mouse |
Background
This antimicrobial gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are characterized by two adjacent cysteines. Similar to other chemokines, the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. It is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high-affinity functional ligand for chemokine receptor 7 (expressed on T and B lymphocytes) and a known receptor for another member of the cytokine family (small inducible cytokine A19). [Provided by RefSeq, Sep 2014]
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