ELK Biotechnology GH rabbit pAb
GH rabbit pAb는 성장호르몬(GH)을 인식하는 토끼 다클론 항체로, IHC, IF, ELISA에 사용 가능하며 높은 특이성과 재현성을 제공합니다. 인간, 쥐, 랫트 시료에 반응하며, -20°C에서 1년 보관 가능합니다.
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ELK Biotechnology GH rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | GH rabbit pAb |
| Alternative Names | Somatotropin (Growth hormone; GH; GH-N; Growth hormone 1; Pituitary growth hormone), Growth hormone variant (GH-V; Growth hormone 2; Placenta-specific growth hormone) |
| Applications | IHC, IF, ELISA |
| Recommended Dilutions | IHC-p: 1:50–200, ELISA: 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein at AA range: 180–217 |
| Storage | -20°C / 1 year |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| GeneID (Human) | 2688 |
| Human Swiss-Prot No. | P01241 / P01242 |
| Cellular localization | Secreted |
| Species Reactivity | Human, Rat, Mouse |
Background
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones, which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17, where they are interspersed in the same transcriptional orientation—an arrangement thought to have evolved by a series of gene duplications. These five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue, unlike the other four genes in the growth hormone locus. Mutations or deletions in the gene can lead to growth hormone deficiency and short stature.
(provided by RefSeq, Jul 2008)
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