ELK Biotechnology DAAM1 rabbit pAb
DAAM1 단백질을 인식하는 토끼 폴리클로날 항체로, WB 및 ELISA에 적합합니다. 세포 골격 및 극성 연구에 활용 가능하며, 사람 및 생쥐 시료에 반응합니다. 합성 펩타이드 면역원으로 제작되었으며, -20°C에서 1년 보관 가능합니다.
- 카탈로그번호
- ES8614-xxxxx (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다ELK Biotechnology · ELK Biotechnology DAAM1 rabbit pAb
제품명
DAAM1 rabbit pAb
제품 개요
Disheveled-associated activator of morphogenesis 1 (DAAM1)에 대한 토끼 폴리클로날 항체입니다. 세포 이동성, 부착, 세포질 골격 재구성 등과 관련된 연구에 유용합니다.
제품 정보
| 항목 | 내용 |
|---|---|
| Product name | DAAM1 rabbit pAb |
| Alternative Names | Disheveled-associated activator of morphogenesis 1 |
| Applications | WB; ELISA |
| Recommended Dilutions | WB 1:500–2000, ELISA 1:10000–20000 |
| Immunogen | Synthetic peptide from human protein (AA range: 400–500) |
| Host | Rabbit |
| Storage | -20°C / 1 year |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 123 kD |
| GeneID (Human) | 23002 |
| Human Swiss-Prot No | Q9Y4D1 |
| Cellular Localization | Cytoplasm; cytoskeleton; cilium basal body; perinuclear |
| Species Reactivity | Human; Mouse |
Background
Cell motility, adhesion, cytokinesis, and other functions of the cell cortex are mediated by reorganization of the actin cytoskeleton. Several formin homology (FH) proteins are associated with these processes. The protein encoded by this gene contains two FH domains and belongs to a novel FH protein subfamily implicated in cell polarity. A key regulator of cytoskeletal architecture, the small GTPase Rho, is activated during development by Wnt/Fz signaling to control cell polarity and movement. The encoded protein is thought to function as a scaffolding protein for the Wnt-induced assembly of a disheveled (Dvl)-Rho complex. It promotes the nucleation and elongation of new actin filaments and regulates cell growth through stabilization of microtubules. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
ELK Biotechnology 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.