ELK Biotechnology CSH1 rabbit pAb
CSH1 rabbit polyclonal antibody는 인간, 랫, 마우스 시료에 반응하며 WB, IHC, IF, ELISA에 사용 가능합니다. 합성 펩타이드(AA 161-210)를 면역원으로 하며, 25kD 밴드를 검출합니다. 성장 조절 관련 호르몬 연구에 적합합니다.
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제품명
CSH1 rabbit pAb
제품 정보
| 항목 | 내용 |
|---|---|
| Alternative Names | CSH1; CSH2 |
| Applications | WB; IHC; IF; ELISA |
| Recommended Dilutions | IHC-p: 1:100–1:300; WB: 1:500–1:2000; ELISA: 1:10000–1:20000 |
| Immunogen | Synthetic peptide from human protein (AA range: 161–210) |
| Species Reactivity | Human; Rat; Mouse |
| Clonality | Polyclonal |
| Isotype | IgG |
| Concentration | 1 mg/ml |
| Observed Band | 25 kD |
| GeneID (Human) | 1442 |
| Human Swiss-Prot No. | P01243 |
| Cellular Localization | Extracellular region; Endoplasmic reticulum; Vesicle; Membrane-bounded vesicle |
| Storage | -20°C, 1 year |
| Host | Rabbit |
Background
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development.
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