Thermo Fisher Scientific MADCAM1 Monoclonal Antibody (OTI2D9), TrueMAB
인간 MADCAM1 단백질을 인식하는 단클론 항체로, Western blot에 최적화됨. Mouse IgG2b 아이소타입이며 비결합형, 동결건조 형태로 제공. 고순도 친화 크로마토그래피 정제, 연구용으로만 사용 가능.
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Applications
- Western Blot (WB)
Tested Dilution: 1:4,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D9 |
| Immunogen | Full-length human recombinant protein of human MADCAM1 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of about 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
The MADCAM1 protein is an endothelial cell adhesion molecule that interacts preferentially with the leukocyte β7 integrin LPAM-1 (α4β7), L-selectin, and VLA-4 (α4β1) on myeloid cells to direct leukocytes into mucosal and inflamed tissues.
It belongs to the immunoglobulin family and is similar to ICAM1 and VCAM1.
At least seven alternatively spliced transcripts encoding different protein isoforms have been identified for this gene, though some full-length variants remain undetermined.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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