Thermo Fisher Scientific Filensin Monoclonal Antibody (OTI3H6)
Filensin 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, Western blot과 IHC(P) 실험에 적합합니다. Human 시료 반응성을 가지며, 고순도 정제 및 안정한 PBS 기반 저장용액으로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3H6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 405–665 of BFSP1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724304 |
Target Information
More than 99% of the vertebrate ocular lens is comprised of terminally differentiated lens fiber cells. Two lens-specific intermediate filament-like proteins, CP49 (phakinin) and filensin, are expressed only after fiber cell differentiation has begun. Both proteins are components of the beaded filament (BF), a unique cytoskeletal structure in lens fibers. Mutations in the BFSP1 gene, which encodes filensin, cause autosomal recessive cortical juvenile-onset cataract. Multiple transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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