Thermo Fisher Scientific TFB2M Polyclonal Antibody
Human TFB2M 단백질에 특이적인 Rabbit Polyclonal Antibody로 Western Blot 및 Immunohistochemistry에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. PBS 기반 저장용액에 포함되어 장기 보관 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 0.04–0.4 µg/mL
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human TFB2M. Recombinant protein control fragment (Product #RP-94418) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2790291 |
Product Specific Information
Immunogen sequence:
FKNLGIEAVP WTADIPLKVV GMFPSRGEKR ALWKLAYDLY SCTSIYKFGR IEVNMFIGEK EFQKLMADPG NPDLYHVLSV IWQLACEIK
Target Information
S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop.
Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM.
Stimulates transcription independently of the methyltransferase activity.
Compared to TFB1M, it activates transcription of mitochondrial DNA more efficiently, while it has less methyltransferase activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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