Thermo Fisher Scientific SIRT5 Polyclonal Antibody
Rabbit polyclonal antibody targeting human SIRT5. Validated for Western blot applications. Preservative-free formulation; sodium azide addition recommended. Suitable for research use only. Maintains stability under refrigerated storage.
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Applications
- Western Blot (WB): Tested dilution 1:500–1:1,000
- Refer to publications for additional validation data.
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to the N-terminus of Human SIRT5 (UniProt ID: Q9NXA8-1, Antigen range: 1–310) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Lot-specific |
| Storage Conditions | 2–8°C up to 1 month; for long-term storage, store at -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2788280 |
Product Specific Information
- Preservative-free formulation.
- Recommended to add sodium azide (final concentration 0.05%–0.1%) to prevent contamination.
- Specificity: Human SIRT5.
Target Information
SIRT5 is a member of the human sirtuin family (Sir2-like proteins) found in both prokaryotes and eukaryotes.
All sirtuins share a conserved core domain with sequence motifs present across species.
These proteins metabolize NAD and may act as mono-ADP-ribosyltransferases.
Sirtuins are implicated in NAD metabolism and histone deacetylation, suggesting a coupled activation mechanism involving NAD and acetylated histones.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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