Thermo Fisher Scientific TNFR2 Polyclonal Antibody
Human TNFR2 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, ICC/IF, ELISA에 사용 가능. 고순도 Affinity Chromatography 정제, 액상 형태로 제공되며 -20°C에서 보관. 세포막 단백질 TNFR2 연구용에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 30–250 of human TNFR2/TNFRSF1B (NP_0010571) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.02 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804140 |
Product Specific Information
Immunogen sequence:
TPYAPEPGST CRLREYYDQT AQMCCSKCSP GQHAKVFCTK TSDTVCDSCE DSTYTQLWNW VPECLSCGSR CSSDQVETQA CTREQNRICT CRPGWYCALS KQEGCRLCAP LRKCRPGFGV ARPGTETSDV VCKPCAPGTF SNTTSSTDIC RPHQICNVVA IPGNASMDAV CTSTSPTRSM APGAVHLPQP VSTRSQHTQP TPEPSTAPST SFLLPMGPSP P
Positive Samples: THP-1
Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha and lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most metabolic effects of TNF-alpha.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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