Thermo Fisher Scientific TNFR2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 30-250 of human TNFR2/TNFR2/TNFRSF1B (NP_0010571) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TNFR2,uniProtId:P20333-1,ncbiNodeId:9606,antigenRange:30-250,antigenLength:461,antigenImageFileName:PA5-87429_TNFR2_P20333-1_Rabbit.svg,antigenImageFileNamePDP:PA5-87429_TNFR2_P20333-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2.02 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2804140

Product Specific Information

Immunogen sequence: TPYAPEPGST CRLREYYDQT AQMCCSKCSP GQHAKVFCTK TSDTVCDSCE DSTYTQLWNW VPECLSCGSR CSSDQVETQA CTREQNRICT CRPGWYCALS KQEGCRLCAP LRKCRPGFGV ARPGTETSDV VCKPCAPGTF SNTTSSTDIC RPHQICNVVA IPGNASMDAV CTSTSPTRSM APGAVHLPQP VSTRSQHTQP TPEPSTAPST SFLLPMGPSP P; Positive Samples: THP-1; Cellular Location: Cell membrane, Single-pass type I membrane protein

Target Information

TNFR2 (tumor necrosis factor receptor superfamily member 1B) is a receptor with high affinity for TNFSF2/TNF-alpha. It has a much lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. TNFR2 mediates most of the metabolic effects of TNF-alpha.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.