Thermo Fisher Scientific CARM1 Monoclonal Antibody (6G9)
CARM1 단백질을 인식하는 Thermo Fisher Scientific의 Mouse Monoclonal Antibody(6G9). Human 시료에 반응하며 ELISA에 적합. 비결합형 액상 형태로 제공되며, -20°C 보관 권장. 연구용으로만 사용 가능.
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Applications
ELISA (ELISA)
- Tested Dilution: 10 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 6G9 |
| Immunogen | CARM1 (NP_954592, 284 a.a. ~ 381 a.a) partial recombinant protein with GST tag. MW of GST tag alone: 26 KDa |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Storage Buffer | Ascites |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
NMFPTIGDVH LAPFTDEQLY MEQFTKANFW YQPSFHGVDL SALRGAAVDE YFRQPVVDTF DIRILMAKSV KYTVNFLEAK EGDLHRIEIP FKFHMLHS
Target Information
Protein arginine N-methyltransferases, such as CARM1, catalyze the transfer of a methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins to form methylated arginine derivatives and S-adenosyl-L-homocysteine.
Protein arginine methylation has been implicated in:
- DNA packaging
- Transcription regulation
- Signal transduction
- mRNA stability
- Metabolism of nascent pre-RNA
- Transcriptional activation
Tissue specificity: Overexpressed in prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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