Thermo Fisher Scientific ICAM-3 Polyclonal Antibody
Human ICAM-3 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western Blot에 최적화되어 있음. 항원 친화 크로마토그래피로 정제된 고순도 제품. 세포 접착 및 면역 반응 연구에 활용 가능. 연구용으로만 사용.
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Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:3,000
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Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to amino acids 312–547 of Human ICAM-3 (CD50, UniProt ID: P32942-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.01 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris Glycine, pH 7, with 10% glycerol |
| Contains | 0.01% Thimerosal |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2547291 |
Product Specific Information
- Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji
- Predicted reactivity: Rhesus Monkey (91%), Chimpanzee (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
CD50 (ICAM-3, intracellular adhesion molecule 3) is a transmembrane glycoprotein expressed by leukocytes. It acts as a counter-receptor for LFA-1 integrin and mediates contact between T cells and antigen-presenting cells. ICAM-3 regulates LFA-1 affinity for ICAM-1, induces T cell activation and proliferation, and plays a crucial role in initiating immune responses. It also interacts with CD209 (DC-SIGN), facilitating communication between dendritic cells and granulocytes.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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