Thermo Fisher Scientific PDCD1 Monoclonal Antibody (OTI3A1), TrueMAB
PDCD1 단백질을 표적으로 하는 Mouse IgG1 단클론 항체로, Human 및 Mouse 시료에 반응합니다. Western blot, ICC/IF, Flow cytometry에 사용 가능하며, 고순도 친화 크로마토그래피로 정제된 동결건조 형태입니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:50 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A1 |
| Immunogen | Full length human recombinant PDCD1 protein produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PDCD1 (Programmed Cell Death 1, PD-1) is an inhibitory receptor expressed on activated T cells. It binds to ligands PDL-1 and PDL-2 on antigen-presenting cells, transmitting inhibitory signals that regulate immune responses. PD-1 plays a key role in preventing autoimmunity by limiting T-cell activation. PD1-deficient mice exhibit hyperactivated immune systems and autoimmune diseases. PD-1 may migrate at a higher molecular weight than predicted in SDS-PAGE.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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