Thermo Fisher Scientific TMEM214 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 1–2 µg/mL

Product Specifications

Product Specific Information

• A suggested positive control is rat brain tissue lysate.
• PA5-20792 can be used with blocking peptide PEP-0906.

Target Information

Transmembrane protein 214 (TMEM214) is a 77 kDa membrane protein widely expressed at high levels.
The gene encoding this protein maps to chromosome 2, at 2p23.3. TMEM214 interacts with LSM1, an SM-like protein, forming a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing.
Although the detailed function of TMEM214 remains unclear, studies suggest it may help explore human host factors involved in infectious diseases such as Dengue fever, West Nile fever, and yellow fever. Multiple isoforms of TMEM214 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.