Thermo Fisher Scientific PAX5 Monoclonal Antibody (OTI3A7), TrueMAB
PAX5 단백질을 인식하는 Mouse Monoclonal 항체로, Western blot 및 IHC(Paraffin) 실험에 적합합니다. Human 시료에 반응하며, 동결건조 형태로 제공됩니다. PBS buffer에 trehalose가 포함되어 안정성이 우수합니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A7 |
| Immunogen | Full length human recombinant protein of human PAX5 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, an additional desalting step is recommended (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
PAX5 is a member of the paired box (PAX) family of transcription factors. These proteins regulate early development, and altered expression can contribute to neoplastic transformation.
PAX5, also known as B-cell lineage specific activator protein (BSAP), is expressed at early but not late stages of B-cell differentiation. Expression is also found in developing CNS and testis, suggesting roles in neural development and spermatogenesis.
Mutations in PAX5 are associated with leukemia and acute lymphoblastic conditions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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