Thermo Fisher Scientific NEK1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human NEK1. Recombinant protein control fragment (Product #RP-91448). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:NEK1,uniProtId:Q96PY6-1,ncbiNodeId:9606,antigenRange:719-864,antigenLength:1258,antigenImageFileName:PA5-54271_NEK1_Q96PY6-1_Rabbit.svg,antigenImageFileNamePDP:PA5-54271_NEK1_Q96PY6-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2644600

Product Specific Information

Immunogen sequence: NLKAQEDEKG KQNLSDTFEI NVHEDAKEHE KEKSVSSDRK KWEAGGQLVI PLDELTLDTS FSTTERHTVG EVIKLGPNGS PRRAWGKSPT DSVLKILGEA ELQLQTELLE NTTIRSEISP EGEKYKPLIT GEKKVQCISH EINPSA

Highest antigen sequence identity to the following orthologs: Mouse - 72%, Rat - 71%.

Target Information

NEK1 is a serine/threonine protein kinase, related to the NIMA cell cycle regulator, and is highly expressed in meiotic germ cells. The kinase may function early in the DNA damage response pathway. NEK1 may also participate in polycystic kidney disease and neural cell development. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.