Thermo Fisher Scientific NEK1 Polyclonal Antibody
Human NEK1 단백질에 특이적인 Rabbit Polyclonal Antibody로, WB, IHC(P), IP에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS/glycerol buffer에 보관. DNA 손상 반응 및 세포 주기 연구에 적합.
- 판매단위
- pk
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human NEK1 (Product #RP-91448) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2644600 |
Product Specific Information
Immunogen sequence:
NLKAQEDEKG KQNLSDTFEI NVHEDAKEHE KEKSVSSDRK KWEAGGQLVI PLDELTLDTS FSTTERHTVG EVIKLGPNGS PRRAWGKSPT DSVLKILGEA ELQLQTELLE NTTIRSEISP EGEKYKPLIT GEKKVQCISH EINPSA
Sequence identity:
- Mouse: 72%
- Rat: 71%
Target Information
NEK1 is a serine/threonine protein kinase related to the NIMA cell cycle regulator, highly expressed in meiotic germ cells. It may function early in the DNA damage response pathway and is implicated in polycystic kidney disease and neural cell development. The protein includes an N-terminal pleckstrin homology domain and a conserved C-terminal OSBP-like sterol-binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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