Thermo Fisher Scientific THOP1 Monoclonal Antibody (2B4)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:1,000

-

ELISA (ELISA)

1:500-1:1,000

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgM, kappa

Class

Monoclonal

Type

Antibody

Clone

2B4

Immunogen

THOP1 (NP_003240.1, 255 a.a. approximately 354 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:Thimet Oligopeptidase,uniProtId:P52888-1,ncbiNodeId:9606,antigenRange:255-354,antigenLength:689,antigenImageFileName:H00007064-M01A_Thimet_Oligopeptidase_P52888-1_House_mouse.svg,antigenImageFileNamePDP:H00007064-M01A_Thimet_Oligopeptidase_P52888-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

See Label

Storage buffer

ascites

Contains

no preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Product Specific Information

Sequence of this protein is as follows: ILKELVTLRA QKSRLLGFHT HADYVLEMNM AKTSQTVATF LDELAQKLKP LGEQERAVIL ELKRAECERR GLPFDGRIRA WDMRYYMNQV EETRYCVDQN

Target Information

A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enzymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.