Thermo Fisher Scientific MUC4 (Mucin 4/Gastric Mucin) Monoclonal Antibody (MUC4/3084)
인체 MUC4 단백질을 인식하는 Mouse monoclonal antibody로, IHC(P), IHC(PFA), Peptide Array 등 다양한 응용에 사용 가능. 단백질 A/G로 정제된 액상형 항체이며, 암 및 점막 관련 연구용으로 적합. 연구용으로만 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Peptide Array (Array)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MUC4/3084 |
| Immunogen | Recombinant fragment (around aa 1730–1864) of human MUC4 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nearly all mucosal surfaces are protected by mucin transmembrane glycoproteins, from bronchioles to corneas to reproductive tracts.
Mucin 4 (MUC4) is membrane-bound and plays an important role in protection and lubrication.
MUC4 expression is aberrant in many carcinomas and sarcomas, including fibromyoxoid sarcoma and pancreatic adenocarcinoma.
Immunohistochemical staining for MUC4 has been discussed as a potential biomarker for detection of these cancers.
MUC4 is notably associated with certain Asian diseases such as Taiwanese infertility, endometriosis, and gallstone formation in Chinese men.
Its dysfunction is implicated in metastatic cancer invasions due to its critical role in mucosal surface protection.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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