
Thermo Fisher Scientific STOML2 Monoclonal Antibody (OTI1F5), TrueMAB
STOML2 단백질을 인식하는 마우스 모노클로날 항체로, Western blot 및 IHC(P)에서 사용 가능. 사람, 마우스, 랫트 반응성. 동결건조 형태로 제공되며, 재구성 후 1 mg/mL 농도. 미토콘드리아 기능 및 세포 반응 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F5 |
| Immunogen | Full length human recombinant protein of human STOML2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
STOML2 is a mitochondrial protein involved in regulating mitochondrial biogenesis and activity.
It stimulates cardiolipin biosynthesis and binds cardiolipin-enriched membranes, recruiting and stabilizing proteins such as prohibitin.
STOML2 contributes to the organization of functional mitochondrial membrane microdomains and plays roles in:
- Cell migration and proliferation
- T-cell activation
- Calcium homeostasis
- Cellular stress response
It is required for mitochondrial hyperfusion, a pro-survival response that enhances ATP production. STOML2 may also regulate plasma membrane domain organization and T-cell receptor signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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