Thermo Fisher Scientific CIDEA Polyclonal Antibody
CIDEA 단백질을 인식하는 Rabbit Polyclonal Antibody로 인간 시료에 반응. IHC 및 ICC/IF에 사용 가능하며, Protein A와 Antigen affinity chromatography로 정제됨. 보존제 무첨가, 장기 보관 시 -20°C 권장.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:200–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to the C-terminus of the Human CIDEA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2787790 |
Product Specific Information
- This product is preservative free.
- It is recommended to add sodium azide to avoid contamination (final concentration 0.05%–0.1%).
- This antibody has specificity for Human CIDEA.
Target Information
This gene encodes the homolog of the mouse protein CIDEA that has been shown to activate apoptosis. This activation of apoptosis is inhibited by the DNA fragmentation factor DFF45 but not by caspase inhibitors. Mice lacking functional CIDEA exhibit higher metabolic rates, increased lipolysis in brown adipose tissue, and higher core body temperatures under cold exposure. These mice are resistant to diet-induced obesity and diabetes, suggesting a role in thermogenesis and lipolysis. Alternatively spliced transcripts have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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