Thermo Fisher Scientific DGCR2 Polyclonal Antibody

Applications and Tested Dilution

• Western Blot (WB): 0.2–1 µg/mL

Product Specifications

Product Specific Information

• Immunogen sequence: AESCYEKSSF LCKRSQTCVD IKDNVVDEGF YFTPKGDDPC LSCTCHGGEP
• Storage recommendation:
  • Short term: 2–8°C, up to 1 week
  • Long term: -20°C, aliquot to prevent freeze–thaw cycles
• Predicted homology:
  Cow 100%; Dog 100%; Guinea Pig 100%; Horse 100%; Human 100%; Mouse 100%; Rabbit 100%; Rat 100%; Zebrafish 86%

Target Information

Deletions of the 22q11.2 region have been associated with multiple developmental defects, including DiGeorge syndrome, velocardiofacial syndrome, conotruncal anomaly face syndrome, and isolated conotruncal cardiac defects (collectively known as CATCH 22).
The DGCR2 gene encodes a putative adhesion receptor protein that may play a role in neural crest cell migration, a process proposed to be altered in DiGeorge syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.