Thermo Fisher Scientific SIGLEC5 Polyclonal Antibody
SIGLEC5 단백질을 인식하는 Rabbit Polyclonal 항체로, Human 및 Mouse 시료에 반응합니다. Western blot과 IHC(Paraffin) 실험에 사용 가능하며, 고순도의 액상 형태로 제공됩니다. 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | - |
| Immunohistochemistry (IHC) | - | View 1 publication |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 | - |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 8–39 amino acids from the N-terminal region of human SIGLEC5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.8 mg/mL |
| Purification | Size-exclusion, Dialysis, Ammonium sulfate precipitation |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C. Avoid freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2189281 |
Target Information
SIGLEC5 is a putative adhesion molecule that mediates sialic acid-dependent binding to cells. It binds both α2,3-linked and α2,6-linked sialic acids. The recognition site may be masked by cis interactions with sialic acids on the same cell surface. SIGLEC5 is expressed by monocytic/myeloid lineage cells and is found at high levels in peripheral blood leukocytes, spleen, and bone marrow, with lower expression in lymph node, lung, appendix, placenta, pancreas, and thymus. It is expressed by monocytes and neutrophils but absent from leukemic cell lines representing early myelomonocytic differentiation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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