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Thermo Fisher Scientific MUC16/CA125 (Ovarian Carcinoma Marker) Monoclonal Antibody ([5E11])
난소암 표지자인 MUC16/CA125를 인식하는 단클론 항체. 사람 시료에 반응하며 IHC(P), IHC(PFA)에 사용 가능. 단백질 A/G 정제, 1 mg/mL 농도의 액상 형태. 연구용으로만 사용, -20°C에서 보관.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | [5E11] |
| Immunogen | Enzymatically glycosylated fragment of human MUC16 recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
Target Information
CA125 determinant is present on a high molecular weight, mucin-like glycoprotein. It is expressed in tissues derived from coelomic and mullerian epithelium, including pleura, pericardium, peritoneum, and reproductive tract epithelium such as fallopian tube, endometrium, and endocervix. Expression is also observed in pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland. CA125 is a well-known marker found in ovarian tumors of serous, endometrioid, or clear cell types, and in adenocarcinomas of mullerian origin.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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