Thermo Fisher Scientific AKAP12 Polyclonal Antibody
AKAP12 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC 등 다양한 응용에 적합합니다. 인체 유래 펩타이드 면역원으로 제조되었으며, 고순도의 Affinity chromatography 정제 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human AKAP12 (Accession Q02952), corresponding to amino acid residues G1749–S1782 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899469 |
Product Specific Information
Antibody detects endogenous levels of total AKAP12.
Target Information
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins that bind to the regulatory subunit of protein kinase A (PKA), localizing the holoenzyme to discrete cellular regions.
This gene encodes an AKAP family member expressed in endothelial cells, fibroblasts, and osteosarcoma cells.
It associates with protein kinases A and C and phosphatase, serving as a scaffold protein in signal transduction.
AKAP12 and RII PKA colocalize at the cell periphery and are involved in cell growth regulation.
Antibodies to this protein may be produced in patients with myasthenia gravis.
Alternative splicing results in two transcript variants encoding different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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