Thermo Fisher Scientific CDK2AP1 Polyclonal Antibody
CDK2AP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal 항체. 인간 시료에 반응하며 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되었고 PBS/glycerol 버퍼에 보관. 세포주기 및 에피제네틱 연구용.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CDK2AP1 Polyclonal Antibody
Applications
- Immunocytochemistry (ICC/IF)
Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CDK2AP1. Recombinant protein control fragment (Product #RP-106793) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2662025 |
Product Specific Information
Immunogen sequence:
ATSSQYRQLLS DYGPPSLGYT QGTGNSQVPQ SKYAELLAII EELGKEI
Highest antigen sequence identity to the following orthologs:
- Mouse: 100%
- Rat: 100%
Target Information
The protein encoded by this gene is a cyclin-dependent kinase 2 (CDK2)-associated protein that negatively regulates CDK2 activity by sequestering monomeric CDK2 and targeting CDK2 for proteolysis. It also interacts with DNA polymerase alpha/primase and mediates phosphorylation of the large p180 subunit, suggesting a regulatory role in DNA replication during S-phase.
Additionally, this protein forms part of the nucleosome remodeling and histone deacetylation (NURD) complex, which epigenetically regulates embryonic stem cell differentiation.
Thus, CDK2AP1 plays roles in both cell-cycle and epigenetic regulation.
Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.