
Thermo Fisher Scientific CHST14 Polyclonal Antibody
CHST14 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 인체 시료에 반응하며 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제된 액상 항체로, 장기 보관 시 -20°C에서 안정적. 연구용으로만 사용 가능.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human CHST14. Recombinant protein control fragment (Product #RP-106795) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664115 |
Product Specific Information
Immunogen sequence:
AYRNKFGEIRE YQQRYGAEIV RRYRAGAGPS PAGDDVTFPE FLRYLVDEDP ERMNEHWMPV YHLCQPCAVH YOrtholog identity:
Highest antigen sequence identity to the following orthologs — mouse 99%, rat 99%.
Target Information
Catalyzes the transfer of sulfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sulfate. Plays a pivotal role in the formation of 4-O-sulfated IdoA blocks in dermatan sulfate. Transfers sulfate to the C-4 hydroxyl of β1,4-linked GalNAc that is substituted with an α-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sulfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA- sequences. Has preference for partially desulfated dermatan sulfate. Addition of sulfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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