Thermo Fisher Scientific Phospho-Acinus (Ser1180) Polyclonal Antibody
인간 ACIN1 단백질의 Ser1180 인산화 부위를 인식하는 Rabbit Polyclonal Antibody. Western blot 및 IHC(Paraffin) 적용 가능. 내인성 인산화 Acinus 검출에 적합하며, 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ACIN1 (Accession Q9UKV3), corresponding to amino acid residues around phosphorylated Ser1180 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2817361 |
Product Specific Information
Antibody detects endogenous levels of Acinus only when phosphorylated at Ser1180.
Target Information
ACINUS (Apoptotic Chromatin Condensation Inducer in the Nucleus) is an inducer of chromatin condensation. It is cleaved by caspase-3 and another unknown protease to generate a small active peptide, p17, which causes chromatin condensation in vitro when added to purified nuclei. ACINUS also induces apoptotic chromatin condensation in cells and is ubiquitously expressed. Three different spliced forms of Acinus have been identified in human and mouse.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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