Thermo Fisher Scientific Prohibitin Polyclonal Antibody
Prohibitin 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. 다양한 응용(WB, IHC, ICC, Flow, ELISA)에 사용 가능. 고순도 Protein A 정제, 1 mg/mL 농도. 인간, 생쥐, 랫트 반응성. 연구용으로만 사용.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| Flow Cytometry (Flow) | 1:20–1:100 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human Prohibitin, amino acids 171–272 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Prohibitin is encoded by an evolutionarily conserved gene that is ubiquitously expressed. It is believed to act as a negative regulator of cell proliferation and may function as a tumor suppressor. Mutations in the PHB gene have been associated with sporadic breast cancer. Prohibitin is expressed as two transcripts differing in the length of the 3′ untranslated region. The longer transcript is more abundant in proliferating tissues and cells, suggesting that this region may serve as a trans-acting regulatory RNA.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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