Thermo Fisher Scientific PGC Polyclonal Antibody
Thermo Fisher Scientific의 PGC Polyclonal Antibody는 인간, 마우스, 랫트 반응성을 가지며 Western blot 및 IHC(P) 실험에 적합합니다. 항원 친화 크로마토그래피로 정제된 고순도 (>95%) 제품으로, 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:1,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 280–330 of Human Pepsin C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2803398 |
Product Specific Information
- Purity is >95% by SDS-PAGE.
Target Information
Pepsin is one of the main proteolytic enzymes secreted by the gastric mucosa. It consists of a single polypeptide chain and arises from its precursor, pepsinogen, by removal of a 41 amino acid segment from the N-terminus. Pepsinogen is synthesized in the stomach lining, and hydrochloric acid, also produced by the gastric mucosa, converts the inactive enzyme and maintains the optimum acidity (pH 1–3) for pepsin function. Pepsin effectively cleaves peptide bonds involving aromatic amino acids and shows broad specificity. Pepsin C differs from pepsinogen and pepsin in amino acid composition, particularly in basic amino acids, glutamic acid, aspartic acid, leucine, and isoleucine.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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