Thermo Fisher Scientific PDE2A Monoclonal Antibody (OTI2A5), TrueMAB
Human PDE2A 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, ICC/IF, Flow Cytometry에 적합. Lyophilized 형태로 제공되며, 1 mg/mL 농도. 연구용으로만 사용 가능하며, 뇌 조직 등에서 PDE2A 발현 연구에 활용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2A5 |
| Immunogen | Full length human recombinant protein of human PDE2A produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform additional desalting using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
PDE2A (phosphodiesterase 2A) is a 100 kDa cyclic nucleotide phosphodiesterase with three isoforms (PDE2A1, PDE2A2, PDE2A3) generated by alternative splicing. It hydrolyzes both cAMP and cGMP, with higher efficiency for cGMP. PDE2A is expressed in various tissues, most abundantly in the brain (cerebellum and neocortex). It is implicated in erectile dysfunction and regulation of endothelial barrier permeability.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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