Thermo Fisher Scientific KCNJ10 Polyclonal Antibody
KCNJ10 단백질을 인식하는 염소 폴리클로날 항체로, Western blot 및 IHC에 적합합니다. 인간, 마우스, 랫트에 반응하며, 동결건조 형태로 제공됩니다. 신경계의 KIR4.1 채널 연구에 유용합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:300–1:2,000 | – |
| Immunohistochemistry (IHC) | 1:300–1:2,000 | – |
| Miscellaneous PubMed (Misc) | – | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Goat / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 330–379 of human KCNJ10 conjugated to blue carrier protein. Target Family: Kir4.1 (KCNJ10), UniProt ID: P78508-1 |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4 °C short term. For long-term storage, store at −20 °C avoiding freeze/thaw cycles. Glycerol (1:1) may be added for stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: KCNJ10.
Target Information
The KIR (inwardly rectifying potassium channel) family allows potassium to flow preferentially into cells.
KIR4.1 (Kir1.2) is highly expressed in the brain, including glial cells, astrocytes, and cortical neurons.
It is also found in myelin-synthesizing oligodendrocytes and is essential for myelination in the developing nervous system.
The human KIR4.1 gene maps to chromosome 1.
KIR4.2 (Kir1.3) is expressed in kidney, lung, heart, thymus, and thyroid during development, mapping to chromosome 21 in the Down syndrome region, and may be implicated in Down syndrome pathogenesis.
KIR5.1 forms functional channels only when coexpressed with KIR4.1 or KIR4.2 in kidney and pancreas.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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