Thermo Fisher Scientific NF2 Polyclonal Antibody
NF2 단백질(Merlin)을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 IHC(Paraffin)에서 사용 가능. 인간에 반응하며, 다양한 종에서도 예측 반응. 항원 친화 크로마토그래피로 정제된 액상형 제품으로 4°C에서 보관.
- 카탈로그번호
- IHC00193x (2개 옵션)
- 판매단위
- pk
카탈로그
2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific NF2 Polyclonal Antibody
Applications
Immunohistochemistry (IHC)
- Tested Dilution: 1:50–1:500
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 550 and the C-terminus (residue 595) of human Neurofibromin 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.10 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, Bovine, Dog, Horse, Rabbit, Pig, Panda, Orangutan, Gorilla, Chinese hamster, and Northern white-cheeked gibbon
Target Information
NF2 encodes a protein, Merlin, that is similar to members of the ERM family of proteins, which link cytoskeletal components with membrane proteins. Merlin interacts with cell-surface proteins, cytoskeletal dynamics regulators, and ion transport proteins.
This gene is highly expressed during embryonic development and in adults is found in Schwann cells, meningeal cells, lens, and nerve.
Mutations in NF2 are associated with neurofibromatosis type II, characterized by nervous system and skin tumors and ocular abnormalities.
Two predominant isoforms and several minor isoforms are produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
(이미지: IHC-00193_NF2_P35240-1_Rabbit.svg, IHC-00193_NF2_P35240-1_Rabbit_PDP.jpeg)
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