Thermo Fisher Scientific DYRK3 Monoclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

-

ELISA (ELISA)

Assay-dependent

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Host/Isotype

Mouse / IgG

Class

Monoclonal

Type

Antibody

Immunogen

Fusion protein, corresponding to amino acids 118-248 of Rat KSR. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:DYRK3,uniProtId:Q4V8A3-1,ncbiNodeId:10114,antigenRange:118-248,antigenLength:586,antigenImageFileName:MA1-91870_DYRK3_Q4V8A3-1_House_mouse.svg,antigenImageFileNamePDP:MA1-91870_DYRK3_Q4V8A3-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2132930

Product Specific Information

Recommended positive controls: 3T3/A31 RIPA lysate.

Target Information

DYRK3 belongs to the DYRK family of dual-specificity protein kinases that catalyze phosphorylation of serine/threonine and tyrosine residues. The members of this family share structural similarity, but differ in their substrate specificity, suggesting their involvement in different cellular functions. DYRK3 is a negative regulator of EPO-dependent erythropoiesis, may place an upper limit on red cell production during stress erythropoiesis. Inhibits cell death due to cytokine withdrawal in hematopoietic progenitor cells. May act by regulating CREB/CRE signaling.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.