Thermo Fisher Scientific NPY Polyclonal Antibody

Applications

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

Reconstitute with 50–100 µL of distilled water, then dilute further in 0.1 M PBS containing 1% BSA and 0.1% sodium azide.
For long-term storage, aliquot and store at -20°C.

Target Information

This gene encodes a neuropeptide widely expressed in the central nervous system. It influences physiological processes such as cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function.
The neuropeptide acts via G protein-coupled receptors to:

• Inhibit adenylyl cyclase
• Activate mitogen-activated protein kinase
• Regulate intracellular calcium levels
• Activate potassium channels

A polymorphism in this gene (leucine 7 to proline) is associated with elevated cholesterol, higher alcohol consumption, and potential risk for metabolic and cardiovascular diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.