Thermo Fisher Scientific NPY Polyclonal Antibody
Rabbit polyclonal antibody recognizing NPY peptide (residues 1–21). Suitable for frozen tissue immunohistochemistry. Lyophilized form; reconstitute before use. Recommended storage at 4°C, long-term at -20°C. For research use only.
- 카탈로그번호
- PA136133
- 판매단위
- pk
카탈로그
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Applications
Immunohistochemistry (Frozen) (IHC (F))
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to residues 1–21 of NPY, conjugated to BSA |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not determined |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2153703 |
Product Specific Information
Reconstitute with 50–100 µL of distilled water, then dilute further in 0.1 M PBS containing 1% BSA and 0.1% sodium azide.
For long-term storage, aliquot and store at -20°C.
Target Information
This gene encodes a neuropeptide widely expressed in the central nervous system. It influences physiological processes such as cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function.
The neuropeptide acts via G protein-coupled receptors to:
- Inhibit adenylyl cyclase
- Activate mitogen-activated protein kinase
- Regulate intracellular calcium levels
- Activate potassium channels
A polymorphism in this gene (leucine 7 to proline) is associated with elevated cholesterol, higher alcohol consumption, and potential risk for metabolic and cardiovascular diseases.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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