Thermo Fisher Scientific AVPR2 Polyclonal Antibody
Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합한 AVPR2 폴리클로날 항체. Human, Mouse, Rat 반응성. Rabbit IgG 기반, Protein A 정제. 고순도 액상 형태로 -20°C 보관.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human AVPR2 (amino acids 65–170) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Avpr2 is a precursor protein consisting of arginine vasopressin and two associated proteins, neurophysin 2 and a glycopeptide, copeptin. Arginine vasopressin is a posterior pituitary hormone synthesized in the supraoptic and paraventricular nuclei of the hypothalamus. Together with its carrier protein, neurophysin 2, it is packaged into neurosecretory vesicles and transported to the neurohypophysis for storage or secretion into the bloodstream.
Avpr2 acts as a growth factor by enhancing pH regulation through acid-base transport systems, has direct antidiuretic action on the kidney, and causes vasoconstriction of peripheral vessels. It can contract smooth muscle during parturition and lactation and is involved in cognition, tolerance, adaptation, and complex sexual and maternal behavior, as well as regulation of water excretion and cardiovascular functions. The activity of Avpr2 is mediated by G proteins that activate adenylate cyclase.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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