Thermo Fisher Scientific SENP6 Polyclonal Antibody
SENP6 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체로, 마우스 시료에서 웨스턴 블롯에 적합합니다. 합성 펩타이드 항원을 사용하였으며, 0.5 mg/mL 농도의 액상 형태입니다. -20°C에서 보관하며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the middle region of human SENP6 (aa 788–837) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2689788 |
Product Specific Information
This target displays homology in the following species:
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%
Target Information
Ubiquitin-like molecules, such as SUMO1, are structurally related to ubiquitin and can be ligated to target proteins in a similar manner. However, covalent attachment of UBLs does not result in degradation of the modified proteins. SUMO1 modification is implicated in the targeting of RANGAP1 to the nuclear pore complex and in stabilization of I-kappa-B-alpha from degradation by the 26S proteasome.
Like ubiquitin, UBLs are synthesized as precursor proteins with additional amino acids following the C-terminal glycine-glycine residues of the mature UBL protein. These tail sequences must be removed by UBL-specific proteases, such as SENP6, before conjugation to target proteins. SENPs also display isopeptidase activity for deconjugation of SUMO-conjugated substrates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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