Thermo Fisher Scientific SDPR Polyclonal Antibody
Thermo Fisher Scientific SDPR Polyclonal Antibody는 인간 및 마우스 SDPR 단백질을 인식하는 토끼 유래 IgG 항체입니다. Western blot과 IHC에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1.0 µg/mL
Immunohistochemistry (IHC)
- Tested Dilution: 1:10,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region of mouse SDPR (aa 80–129) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2688321 |
Product Specific Information
This target displays homology in the following species:
- Cow: 100%
- Goat: 86%
- Guinea Pig: 86%
- Horse: 100%
- Human: 100%
- Mouse: 100%
- Pig: 100%
- Rabbit: 100%
- Rat: 100%
Target Information
The serum deprivation-response protein (SDPR) is a calcium-independent phospholipid-binding protein whose expression is increased in serum-starved cells. SDPR is a substrate for protein kinase C (PKC) phosphorylation and recruits the polymerase I and transcript release factor (PTRF) to caveolae. Removal of this protein causes caveolae loss and its over-expression results in caveolae deformation and membrane tubulation. Both SDPR and PTRF, as well as the other member of the cavin family PRKCDBP, were downregulated in breast cancer cell lines and breast tumor tissue, suggesting that expression of the cavin family proteins could be a useful prognostic indicator of breast cancer progression.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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