Thermo Fisher Scientific Human NAIP Synthetic Peptide
인간 NAIP 단백질의 카복시 말단 13 아미노산 서열에 해당하는 합성 펩타이드. 항체 PA5-20063의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2)와 0.1% BSA, 0.02% sodium azide 함유. -20°C에서 보관.
- 카탈로그번호
- PEP0182
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 13 amino acids near the carboxy terminus of human NAIP.
PEP-0182 can be used as a blocking peptide with polyclonal antibody PA5-20063.
Target Information
Neuronal apoptosis inhibitor protein (NAIP) was the first human inhibitor of apoptosis protein (IAP) identified and was discovered by its association with the neurodegenerative disorder spinal muscular atrophy. Members of the IAP family contain one to three copies of an approximately 70 amino acid motif termed baculovirus IAP repeat (BIR); these BIRs promote protein-protein interactions with various caspases such as caspase-3, -7, and -9 as well as members of the TRAF family of signal molecules. Unlike other IAPs, NAIP requires ATP to bind caspase-9 and is not inhibited by the IAP-inhibiting molecule Smac/DIABLO, suggesting that NAIP is unique among the IAPs in its regulation of activity. Although only one human NAIP protein has been identified, other shorter NAIP mRNA transcripts have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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