Thermo Fisher Scientific IL17RA VHH-8His-Cys-tag Recombinant Alpaca Monoclonal Antibody (SAA1266)
Recombinant alpaca monoclonal antibody targeting human IL17RA (CD217). Compatible with direct ELISA assays. Purified via metal-chelate chromatography, supplied in PBS without preservative. Stable at 4°C short term and -20°C for long term storage.
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Applications
- ELISA (assay-dependent)
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Alpaca / VHH |
| Expression System | CHO cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | SAA1266 |
| Immunogen | Recombinant Human CD217 / IL17RA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Metal-chelate chromatography |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
Product Specific Information
- Compatible with Direct ELISA
Target Information
Interleukin 17A (IL-17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It induces maturation of CD34-positive hematopoietic precursors into neutrophils.
IL-17RA is a type I membrane glycoprotein that binds IL-17A and IL-17F with low affinity.
IL-17A and IL-17RA are implicated in inflammatory and autoimmune diseases such as rheumatoid arthritis.
Defects in IL-17RA cause familial candidiasis type 5 (CANDF5), a rare disorder with altered immune responses and impaired fungal clearance.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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