Thermo Fisher Scientific ALKBH7 Polyclonal Antibody
ALKBH7 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC/IF에 적합합니다. 인간, 마우스, 비인간 영장류에 반응하며, Affinity chromatography로 정제된 액상 제품입니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human ALKBH7 (Accession Q9BT30), corresponding to amino acid residues E51–Q101 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2852837 |
Product Specific Information
Antibody detects endogenous levels of total ALKBH7.
Target Information
ALKBH7 (alkB, alkylation repair homolog 7), also known as SPATA11, is a 221 amino acid protein belonging to the alkB family.
ALKBH7 is one of many homologs of the Escherichia coli protein AlkB, which protects DNA and RNA from damage caused by environmental methylating compounds by directly reversing 1-methyladenine (1-meA) and 3-methylcytosine (3-meC) lesions.
The enzyme acts by oxidative demethylation, utilizing ferrous iron and alpha-ketoglutarate as cofactors, and molecular oxygen as the oxidizing agent.
ALKBH7 is encoded by a gene located on human chromosome 19, which houses approximately 1,400 genes and has the greatest gene density among human chromosomes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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