Thermo Fisher Scientific IRF4 Monoclonal Antibody (A7C12)
IRF4 단백질을 인식하는 Mouse IgG1 단클론 항체로, IHC(P)에서 1:2,000 희석 비율로 검증됨. Human 시료에 반응하며, Protein G로 정제된 액상 형태. 4°C 단기 보관 및 -20°C 장기 보관 권장. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:2,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | A7C12 |
| Immunogen | Synthetic peptide within human MUM1 aa 402–451/451 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.1% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2931405 |
Target Information
The IRF (interferon regulatory factor) family of transcription factors are characterized by a unique tryptophan pentad repeat DNA-binding domain. IRFs regulate interferon responses to viral infection and control interferon-inducible gene expression. IRF4 is lymphocyte-specific and negatively regulates toll-like receptor (TLR) signaling, critical for innate and adaptive immune activation. A chromosomal translocation involving IRF4 and the IgH locus, t(6;14)(p25;q32), may contribute to multiple myeloma. Alternatively spliced transcript variants have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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