Applied Biosystems™

UK Biobank Axiom™ Array Kit

The UK Biobank Axiom Array was designed by and for thought leaders in the human genetics community for high-throughput, high-value자세히 알아보기

The UK Biobank Axiom Array was designed by and for thought leaders in the human genetics community for high-throughput, high-value genotyping of large sample cohorts to explore the genetics of complex diseases and translational research with a single comprehensive low-cost solution. The 96-format array plate allows for genome-wide genotyping of large sample collections such as those screened at biobanks, genome centers, and core labs. This array kit includes the 1x96-format array plate, as well as an Axiom 2.0 Reagent Kit and Axiom GeneTitan Consumables Kit.

GWAS
• Intelligent marker selection enables imputation of millions of additional SNPs
• The genomic content module of each array is optimized for specific populations and is customizable to any 1000 Genomes population study by adding additional markers of your choosing

Pharmacogenomic markers
• Markers were selected to represent phases of absorption, distribution, metabolism, and excretion (ADME)

Inflammation and HLA
• Contains markers with evidence for association with autoimmune and inflammation
• Covers variants in genes in the HLA and KIR regions known to be important in immune response

Exome
• Rare, non-synonymous coding SNPs and indels in protein coding regions of the genome
• A majority of variants are rare with minor allele frequency (MAF) <1%
• Newly discovered loss-of-function content
• SNPs and indels identified from a sequencing initiative of 26,000 individuals
• Known disease-causing mutations

eQTLs
• Markers that have known associations to RNA expression traits
• Captures unique eQTLs contained in the NCBI Genotype-Tissue Expression (GTEx) eQTL database, GEUVIDAS project, and several other discovery projects

Human disease
• Alzheimer-s disease, including coverage of ApoE
• Blood phenotypes
• Cancer common variants
• Cardiometabolic

Choose your content
• Order the pre-designed array and customize it with markers of your choice
• Custom markers may be de novo or selected from the Axiom Genomic Database of genotype-tested markers

Please note: Reagent kits do not include plastic consumables required to run the assay on the Beckman Biomek™ FXP Target Prep Express System. Please contact us for a list of required plastic consumables.

사양

유형Array Kit

어레이Genotyping

어레이 수96 arrays

형식96-array Plate

종Human

용도(애플리케이션)Microarray Analysis

제품라인Axiom™

수량1 each

배송 조건Approved for shipment at Room Temperature or on Wet or Dry Ice

Unit SizeEach