Thermo Fisher Scientific SRAG Polyclonal Antibody
Rabbit polyclonal antibody recognizing human SRAG (CHTOP) protein. Validated for WB and IP applications. Predicted cross-reactivity with mouse, rat, and bovine. Supplied as unconjugated liquid, 1 mg/mL concentration. For research use only, not ...
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Applications
| Application | Tested Dilution | Notes |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,500 | |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Property | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of Human Small Protein Rich in Arginine and Glycine (SRAG) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4 °C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse, Rat, and Bovine
Target Information
CHTOP (Small Protein Rich in Arginine and Glycine) is a small nuclear protein characterized by an arginine- and glycine-rich region. It may play an important role in regulating fetal globin gene expression and activating estrogen-responsive genes.
Studies suggest that CHTOP binds 5-hydroxymethylcytosine (5hmC) and associates with an arginine methyltransferase complex (methylosome), promoting methylation of arginine 3 of histone H4 (H4R3) and activation of genes involved in glioblastomagenesis.
Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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