Thermo Fisher Scientific TFPI Polyclonal Antibody
Rabbit polyclonal antibody recognizing human TFPI. Validated for Western blot and frozen tissue IHC. Predicted cross-reactivity with multiple species. Supplied as 1 mg/mL liquid form, unconjugated, stored at 4°C or -20°C. For research use only.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1 µg/mL | - |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay-dependent | - |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 1–100 of Human TFPI |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10981512 |
Product Specific Information
This antibody is predicted to react with rat, cow, chimpanzee, rhesus monkey, and orangutan based on sequence homology.
Target Information
Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. TFPI is glycosylated and predominantly found in the vascular endothelium and plasma, both in free form and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa–TF complex, which activates additional proteases (factors IX and X) and leads to fibrin clot formation. TFPI inhibits activated factor X and VIIa–TF proteases in an autoregulatory loop.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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