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Thermo Fisher Scientific XPF Monoclonal Antibody (OTI1B2), TrueMAB
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인간 XPF 단백질을 인식하는 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, 안정적 PBS/BSA/glycerol 저장 버퍼 구성. DNA 복구 관련 연구용으로 적합.
- 판매단위
- pk
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마지막 업데이트 2025. 08. 05. 오전 12:47
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Thermo Fisher Scientific TA503262 XPF Monoclonal Antibody (OTI1B2), TrueMAB 100 ul pk판매 단위 pk ·
재고 확인 필요
600,200원VAT 포함 660,220원
Thermo Fisher Scientific · Thermo Fisher Scientific XPF Monoclonal Antibody (OTI1B2), TrueMAB
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1B2 |
| Immunogen | Full length human recombinant protein of human ERCC4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The structure-specific ERCC1/XPF endonuclease complex is implicated in the repair of two distinct types of lesions in DNA:
- Nucleotide excision repair (NER) for UV-induced lesions and bulky chemical adducts
- Recombination repair of genotoxic interstrand cross-links
NER mechanism involves dual incisions on both sides of the damage catalyzed by two nucleases. In mammalian cells, XPG cleaves 3' of the DNA lesion while the ERCC1/XPF complex makes the 5' incision. ERCC1/XPF probably plays a role in processing partially processed recombination intermediates.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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