Thermo Fisher Scientific GluR1 Monoclonal Antibody (RH95)
GluR1 단백질을 인식하는 RH95 클론의 마우스 단클론 항체로, Western blot 및 ICC/IF에 적합합니다. 마우스와 랫트 시료에 반응하며, Protein G로 정제된 액상 형태입니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse, Rat |
| Published Species | Mouse |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | RH95 |
| Immunogen | Synthetic peptide corresponding to the N-terminal region of rat GRIA1 conjugated to KLH |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | ~1.0 mg/mL |
| Purification | Protein G |
| Storage Buffer | 0.01M HEPES, pH 7.5, with 0.15M NaCl, 0.1mg/mL BSA, 50% glycerol |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539491 |
Product Specific Information
This antibody contains enough material to conduct 10 mini-Western blots.
Target Information
GluR1 (glutamate receptor 1) is an ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of L-glutamate induces a conformational change that opens the cation channel, converting the chemical signal to an electrical impulse. The receptor then rapidly desensitizes into an inactive state with a bound agonist. In the presence of CACNG4, CACNG7, or CACNG8, GluR1 shows resensitization characterized by delayed current flux accumulation upon continued glutamate application.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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