Thermo Fisher Scientific CAP-18 Polyclonal Antibody
Thermo Fisher CAP-18 Polyclonal Antibody는 사람 Cathelicidin 항균 펩타이드를 인식하는 토끼 유래 항체입니다. Western blot 및 IHC에 적합하며, 동결건조 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 가능하며 연구용으로만 사용됩니다.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:2,000 | - |
| Immunohistochemistry (IHC) | 1:100–1:2,000 | - |
| Miscellaneous (PubMed) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from aa region 10–60 of human CAP-18 conjugated to blue carrier protein. Target family: Cathelicidin (UniProt ID: P49913-1, NCBI Node ID: 9606). Antigen range: 10–60. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water.
- Centrifuge to remove any insoluble material.
- Specificity: Cathelicidin antimicrobial peptide.
Target Information
Cathelicidin is an epithelial-derived antimicrobial protein found in specific granules of polymorphonuclear leukocytes of bone marrow, testis, and neutrophils.
Cathelicidins are a family of antimicrobial peptides characterized by conserved pro-peptide sequences identified in epithelial tissues and some myeloid cells of humans and animals.
LL-37/hCAP-18 is the only Cathelicidin found in humans and is expressed in inflammatory and epithelial cells.
These molecules are essential for defense against invasive bacterial infection in skin.
Besides their direct antimicrobial function, Cathelicidins play roles in innate and adaptive immunity, including endotoxin neutralization, angiogenesis, wound healing, and promoting neutrophil chemotaxis and mast cell recruitment.
Cathelicidin antimicrobial peptides qualify as prototypes of innovative drugs that may be used to treat infection and/or modulate immune response.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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