Thermo Fisher Scientific NR2E1 Monoclonal Antibody (4D2)
NR2E1(TLX) 단백질을 인식하는 Mouse monoclonal antibody(4D2)로 인간 시료에 반응합니다. ICC/IF 및 ELISA에 적합하며, Affinity chromatography로 정제된 액상 제품입니다. 연구용으로만 사용되며, -20°C에서 보관하십시오.
- 카탈로그번호
- H00007101-M06
- 판매단위
- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 10 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 4D2 |
| Immunogen | NR2E1 (NP_003260, 249–342 a.a.) partial recombinant protein with GST tag (MW of GST tag alone: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein:
NGDNTDSQKL NKIISEIQAL QEVVARFRQL RLDATEFACL KCIVTFKAVP THSGSELRSF RNAAAIAALQ DEAQLTLNSY IHTRYPTQPC RFGK
Target Information
Nuclear receptor TLX (NR2E1) is a NR2 hepatocyte NF4-like receptor involved in anterior brain differentiation, retinal development, and vision. TLX targets genes such as RAR beta2 and Pax2 during retinal development. Homozygous TLX mutant mice display reduced forebrain development and increased aggression. Deletion of TLX locus leads to cerebral hypoplasia, blindness, and extreme aggression. TLX expression is documented in mouse brain and eye, and ESTs have been isolated from normal human brain libraries.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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