Thermo Fisher Scientific SSX2 Polyclonal Antibody
SSX2 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot, ICC/IF, Flow Cytometry에 사용 가능. Human 시료 검증 완료. 고순도(>95%) 정제 항체로 연구용에 적합. 단기 4°C, 장기 -20°C 보관 권장.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 | - |
| Flow Cytometry (Flow) | - | 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant full length Human SSX2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720816 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using an epitope-specific immunogen. The purity is >95% as determined by SDS-PAGE.
Target Information
SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins, which may function as transcriptional repressors. These proteins can elicit spontaneous humoral and cellular immune responses in cancer patients and are potential targets for cancer vaccine-based immunotherapy.
SSX1, SSX2, and SSX4 genes are involved in the t(X;18) translocation found in all synovial sarcomas, resulting in fusion of the synovial sarcoma translocation gene on chromosome 18 with one of the SSX genes on chromosome X. The resulting hybrid proteins are likely responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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